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Research InterestsAssociate Professor Colleen Loo | | (Position Details) | | Phone 02 9113 2039 | | Email | | Qualifications MB BS UNSW MD, FRANZCP |
| | | School/Unit |
| School of Psychiatry | | http://psych.med.unsw.edu.au/
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| | Broad Research Areas | |
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Psychiatry
Neuroscience
Clinical Research
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| | | | Specific Research Keywords | |
| transcranial magnetic stimulation
electroconvulsive therapy
depression
Transcranial direct current stimulation
Brain Sciences
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| | | | Research Interests | |
| Novel non invasive brain stimulation techniques offer exciting new potential to probe the neurobiology of psychiatric disorders, as well as possible new avenues for treating psychiatric disorders. Our team at UNSW, based at the Black Dog Institute (Randwick), has expertise in transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS). Current research streams are:
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| | | | ILP Research Interests (Will supervise ILP students) |
| Depression
Depressive Disorder
Mood Disorders
Psychiatric Disorders
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| | | | Teaching Interests | |
| A/Prof Loo is the course convenor for the UNSW psychiatry program for 5th and 6th year medical students | |
| | | | Society Memberships & Professional Activities | |
| Fellow, Royal Australian and NZ College of Psychiatrists
Member, Editorial Board, Journal of ECT.
Member, Australasian Society for Psychiatric Research
Member, NSW Health ECT Standards Working Party | |
| | | | Funding Sources | |
| -Grants from:
National Health and Medical Research Council (Australia)
NSW Schizophrenia Fellowship
Rebecca Cooper Medical Research Foundation
Pfizer Neuroscience Research Grant
National Alliance for Research on Schizophrenia and Depression (NARSAD)
Australian Rotary Health Research Fund | |
| | | | Other Postgraduate Research | |
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PhD student: Modelling brain stimulation (co-supervisor)
Masters, NSW Institute of Psychiatry: Use of ketamine in Electroconvulsive Therapy | |
| | | | Key works/Publications | |
| Loo C, Mitchell P, Sachdev P, McDarmont B, Parker G & Gandevia S. A double-blind controlled investigation of transcranial magnetic stimulation for the treatment of resistant major depression. American Journal of Psychiatry 1999;156:946-948.
Loo C, Taylor J, Gandevia S, McDarmont B, Mitchell P & Sachdev P. Transcranial magnetic stimulation (TMS) in controlled treatment studies: Are some “sham” forms active? Biological Psychiatry 2000; 47:325-331.
Loo C, Sachdev P, Elsayed h, McDarmont B, Mitchell P, Wilkinson M , Parker G & Gandevia S. Effects of a two to four-week course of repetitive transcranial magnetic stimulation (rTMS) on neuropsychological functioning, EEG and auditory threshold in depressed patients. Biological Psychiatry 2001; 49:615-623.
Sachdev P, McBride R, Loo C, Mitchell P, Malhi G & Croker V. Right versus left prefrontal transcranial magnetic stimulation for obsessive-compulsive disorder: a preliminary investigation. Journal of Clinical Psychiatry 2001; 62 (12) 981-984.
Loo C, Mitchell P, Croker V, Malhi G, Wen W, Gandevia S, Sachdev P. Double-blind controlled investigation of bilateral prefrontal transcranial magnetic stimulation for the treatment of resistant major depression. Psychological Medicine, 2003; 33(1):33-40.
Loo C, Sachdev P, Haindl W, Wen W, Mitchell P, Croker V, Malhi G. !5 Hz and 1 Hz transcranial magnetic stimulation have different acute effects on regional cerebral blood flow in depressed patients. Psychological Medicine 2003; 33:997-1006.
Loo C, Mitchell P. A review of the efficacy of transcranial magnetic stimulation (TMS) treatment for depression, and current and future strategies to optimize efficacy. Journal of Affective Disorders 2005; 88 (3):255-267
Loo C, Schweitzer I, Pratt C. Recent Advances in Optimising Electroconvulsive therapy. Royal Australian and New Zealand Journal of Psychiatry 2006; 40: 632-8.
Loo C, McFarquhar T, Walter G. Transcranial Magnetic Stimulation in adolescent depression. Australasian Psychiatry 2006; 14(1): 81-85.
Mitchell PB and Loo CK. Transcranial Magnetic Stimulation for Depression. Australian and New Zealand Journal of Psychiatry 2006; 40: 406-413.
MacPherson RD, Loo CK & Barratt N. Anaesthesia for Electroconvulsive Therapy in patients with Cardiac Pacemakers. Anaesthesia and Intensive Care 2006; 34 (4) 470-4.
Taylor JL & Loo CK. Stimulus waveform influences the efficacy of repetitive transcranial magnetic stimulation. Journal of Affective Disorders 2007; 97:271-276.
Loo CK, Mitchell PB, McFarquhar T, Malhi GS & Sachdev PS. A Sham-Controlled Trial of the Efficacy and Safety of Twice-Daily rTMS In Major Depression. Psychological Medicine 2007; 37 (3): 341-349.
O’Reardon J, Solvason H, Janicak P, Sampson S, Isenberg K, Nahas Z, McDonald W, Avery D, Fitzgerald P, Loo C, Demitrack M, George M, & Sackeim H. Efficacy and safety of transcranial magnetic stimulation therapy in the acute treatment of major depression: A multi-site randomized controlled trial. Biological Psychiatry 2007; 62 (11): 1208-1216.
Loo CK, McFarquhar T & Mitchell P. A review of the safety of repetitive transcranial magnetic stimulation as a clinical treatment for depression. International Journal of Neuropsychopharmacology. (Epub 20.9.07. Accepted 10/2/07).
Sachdev P, Loo C, Mitchell P, McFarquhar T & Malhi G. Repetitive Transcranial Magnetic Stimulation for the Treatment of Obsessive Compulsive Disorder: A double blind controlled investigation. Psychological Medicine 2007; 37 (11): 1645-1650
Loo CK, Sheehan P, Pigot M, Lyndon W. A Report on Mood and Cognitive Outcomes With Right Unilateral Ultrabrief Pulsewidth (0.3ms) ECT and Retrospective Comparison with Standard Pulsewidth Right Unilateral ECT. Journal of Affective Disorders 2007; 103: 277-281.
Loo C. The NSW Mental Health Bill 2007: Implications for the provision of electroconvulsive therapy in NSW. Australasian Psychiatry 2007; 15(6): 457-464.
MacPherson R & Loo C. Cognitive impairment following ECT - does the choice of anesthetic agent make a difference? Journal of ECT (in press, accepted 27.9.07)
Pigot M, Andrade C & Loo C. Pharmacological attenuation of ECT-induced cognitive deficits: theoretical background and clinical findings. Journal of ECT (accepted 7.11.07).
Loo C. Cognitive Outcomes in Electroconvulsive Therapy: Optimising Current Clinical Practice and Researching Future Strategies. (Editorial) Journal of ECT (accepted 19.12.07, in press). | |
| | | | Further Information | |
| http://www.blackdoginstitute.org.au/ | |
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