Research Interests
Scientia Professor Perminder Sachdev |
| (Position Details) |
| Phone Please contact School/Unit |
| Qualifications MB BS, MD, PhD UNSW, FRANZCP |
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| School/Unit |
| School of Psychiatry |
| www.med.brainage.unsw.edu.au
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| Broad Research Areas | |
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Ageing
Neuropsychology
Neuroscience
Psychiatry
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| Specific Research Keywords | |
| Ageing
Drug-induced movement disorders
Dementia
Imaging
Neurodegenerative Diseases
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| Research Interests | |
| There are broad interests in the field of Neuropsychiatry. Our major focus is on ageing and cognition,and I head the Brain and Ageing program. We have large longitudinal studies of ageing including: Memory and Ageing Study, Older Australian Twins Study, PATH Through Life Study, Sydney Centenarian Study and the Sydney Stroke Study. These studies examine MVI, Alzheimer's disease, Vascular Cognitive Impairment and Vascular Dementia, as well as Cognitive Ageing in healthy individuals. We have a number of studies that involve neuroimaging (MRI, MRS, pMRI, fMRI and SPECT) in dementia, mild cognitive impairment, fronto-temproal dementia, stroke, OCD, anorexia nervosa, etc. We also have a number of studies involving Transcranial Magnetic Stimulation (TMS) and transcranail direct current stimulation (tDCS) for both treatment and as an investigational tool in neuropsychology. We have an interest in exploring novel treatments, including Vagus Nerve Stimulation for depression. I am also the Executive Director of the Stem Cell Laboratory with a focus on neural stem cells.
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| ILP Research Interests (Will supervise ILP students) |
| Diseases And Disorders
Psychiatric Disorders
Psychology
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| Project Topics for current Honours Students |
| A study of microbleeds in community based elderly individuals.
Diffusion tensor imaging as an early marker of cognitive impairment and dementia. | |
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| Teaching Interests | |
| Our particular interest is in the teaching of Neuropsychiatry for both undergraduates and postgraduates.
A Fellowship program for Neuropsychiatry has been developed. | |
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| Funding Sources | |
| NH&MRC
ARC
Rebecca Cooper Foundation
Pacific Research Foundation | |
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| Other Postgraduate Research | |
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-A number of projects in the genetics and proteomics of dementia and ageing are being developed.
We have recently established a Stem Cell laboratory with a focus on neural stem cells for neurodegenerative diseases. | |
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| Key works/Publications | |
| Sachdev PS. Akathisia and restless legs. New York: Cambridge University Press, 1995.
Sachdev P, Kruk J. Clinical characteristics and predisposing factors in acute drug-induced akathisia. Arch Gen Psychiatry 1994; 51:963-974.
Looi JCL, Sachdev P. Differentiation of vascular dementia from AD on neuropsychological tests. Neurology 1999; 53(4):670-678.
Sachdev P, Brodaty H. Quantitative study of signal hyperintensities on T2-weighted magnetic resonance imagining in late-onset-schizophrenia. Am J Psychiatry 1999; 156:1958-1967.
Sachdev PS. The Ageing Brain. Swets & Zeitlinger BV, Lisse, The Netherlands (in press). | |
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| Attachments | |
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Publications_full.doc | |
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| Further Information | |
| www.med.npi.unsw.edu.au | |
Profile last updated: 26/08/2009
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