Browse Research Interests

Hide details for [<a name="Ageing"></a><A HREF="../page/Research%20Interests%20Listing?OpenDocument&start=1&count=1000&Expand=1 Ageing
Dr Tracy Anderson
    School of Psychiatry
    Statement of Interests:
    Dr Anderson works as a Research Fellow for the NHMRC funded Brain and Ageing Program Grant. As part of the program grant team she works closely with Professors in the School of Psychiatry who specialize in geriatric psychiatry, neuropsychiatry, epidemiology, psychiatric classification and health policy. Her fellowship is aimed at exploring epidemiological datasets, considering classification issues, and generating metrics important to health policy within the context of ageing and age-related diseases.
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Dr Divya Bhargav
    St George Clinical School
    Statement of Interests:

    In the field of cartilage biology and regeneration of the intervertebral disc
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Professor Henry Brodaty AO
    School of Psychiatry - Dementia Collaborative Research Centre
    Statement of Interests:

    1)Dementia, particularly Alzheimer's disease: a) how to improve its detection by General Practitioners; b) the effects on family carers and on how best to help them; c) trials of new drugs for the treatment of Alzheimer's disease; d) ways to improve quality of life in people with dementia and e) reduce behavioural and psychiatric complications. 2) Nursing homes: In Australia there are about 75,000 nursing home beds for which the total budget exceeds $2 billion per annum. Over two thirds of nursing home residents have dementia and they exhibit high rates of behavioural disturbances which are distressing to themselves, their families and the staff. We have been conducting a trial of different models of care to help these residents and also been investigating the use of new drugs for the treatment of agitation and psychosis in nursing homes. 3) What predicts cognitive decline in older people? We are conducting a population based study of >1000 older people to discover what are risk and protective factors.
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Professor Elizabeth Burcher
    School of Medical Sciences - Department of Pharmacology
    Statement of Interests:

    a) neurochemicals in human intestine: alterations in disease. b) neurochemicals in the human bladder: relevance to urinary incontinence. c) urothelium of the pig bladder as a model for human bladder studies.
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Dr David Burke
    School of Public Health and Community Medicine
    Statement of Interests:

    Involved in research looking at the way vascular risk factors and vascular pathology effect the expression of various types of cognitive impairment and dementia, and in ways of preventing and treating these. Involved in research looking at the role cognitive impairment in precipitating and perpetuating homelessness in elderly people.
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Associate Professor Gideon Caplan
    Prince of Wales Clinical School - Department of Medicine
    Statement of Interests:

    The delivery of acute health services has potential benefits and side effects of an order of magnitude greater than most pharmaceutical agents, yet are rarely vigorously studied. It may be possible to manipulate these effects by, for example, the substitution for care in the hospital with care at home, during the acute or post acute phases. This would bring benefits for health outcomes, patient satisfaction and costs to the health system which need to be defined. Delirium is the most common problem bedevilling older people in hospital. Yet little is understood about the basic pathophysiology of delirium. Using a multidisciplinary, bedside to lab bench approach, we hope to unlock the mystery of delirium.
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Professor Daniel Chan
    South Western Sydney Clinical School
    Statement of Interests:
    Daniel KY Chan is a senior staff specialist and director of Aged Care and Rehabilitation at Bankstown-Lidcombe Hospital. He is also a conjoint Professor of Geriatrics at the University of New South Wales and an adjunct Professor at the University of Western Sydney. He has qualifications in clinical practice (FRACP, FHKCP), research (MD) and health service management (MHA, AFCHSE). He has been involved with many molecular biology, epidemiologyical, Parkinson's disease, stroke and health service related research. He has had 90 + publications in journals, about two-fifth of these as first author. Many are internationally reputable journals, some highly prestigious. Some of the best journals include New England Journal of Medicine (Impact Factor (IF 44.02, first author) , the top journals in neurology: “Neurology” (IF 5.973, first author), “Archives of Neurology” (IF: 4.835, three papers, first author once and second author once); “Annals of Neurology” (IF: 8.097, co-author), “Journal of Neurology Neurosurgery and Psychiatry” (IF: 3.11, first author) as well as top journals in Geriatrics: “Journal of the American Geriatric Society” (IF: 3.361, most senior author), “Journals of Gerontology” (IF 4.122, first author) and “Age & Ageing” (IF: 1.646, three papers, once first author and twice second author). He is also actively involved in the research area of stroke with publications in reputable journals: including JAGS (IF 3.361), Acta Neurologica Scandinavica (IF 1.712), Neuroepidemiology (IF 1.758) and Medical Journal of Australia (IF 2.0) (Publication list no 6,9,10,15,30,35). He has published a position statement - “Dysphagia and aspiration in older people” on the website on behalf of the Australian Society for Geriatrics Medicine (Publication list no 18). He has been successful in securing in excess of $2million from various competitive grants in recent years. Sources of grants include: NHMRC (ID 510275, CIA; ID 358372, CIF), Hong Kong Research Council; New South Wales Health Department; Pathway Home for elderly(Commonwealth); Australian Council for Safety and Quality in Health Care (Commonwealth); Royal Australasian College of Physicians (mostly as first applicant.
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Associate Professor Jacqueline Close
    Prince of Wales Clinical School
    Statement of Interests:

    Falls and fracture prevention in older people through: a)the systematic identification of risk factors b)the testing of interventions through RCTs c)application of the evidence in the routine clinical setting
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Dr Jeffrey Cohen
    School of Public Health and Community Medicine
    Statement of Interests:

    Role of Spirituality in Health Care; Faith and Mental Health
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Dr Brian Draper
    School of Psychiatry
    Statement of Interests:
    My interests are on clinical aspects of mental health problems in old age. My main focus is dementia including behavioural and psychological symptoms, carer stress and mild cognitive impairment. I head the 'special groups' node of the Dementia CRC based at UNSW which focuses on dementia in younger persons, Indigenous persons, and persons from Culturally and Linguistically Diverse backgrounds. I am also collaborating with the Australian Institute of Health & Welfare on a NHMRC funded study of the transition of persons with dementia through acute hospitals. Suicidal behaviour is another interest with collaborative work funded by ARC and NHMRC being undertaken with colleagues around Australia and internationally.
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Emeritus Professor Fred Ehrlich
    School of Public Health and Community Medicine
    Statement of Interests:

    The impact of potential secondary gain on the prospects of rehabilitation and the display of signs of malingering or the adoption of abnormal illness behaviour preventing accurate assesssment of the purely physical components of disability.
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Dr Shuli Futeran
    School of Psychiatry
    Statement of Interests:
    Mental Health and the Ageing
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Mr Clayton Gilbert
    Medical Administration - Medicine Computing Support Unit
    Statement of Interests:

    For administrative purposes only.
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Associate Professor Peter Gonski
    St George Clinical School
    Statement of Interests:

    In aged care,clinical review of various geriatric syndromes and their management are of particular interest.Hospital admission and discharge outcomes are also being studied.
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Dr Gilles Guillemin
    St Vincent's Clinical School
    Statement of Interests:

    Involvement of tryptophan (an essential amino acid) and its derived molecules (kynurenines) in neurodegenerative diseases such as Alzheimer’s disease, amyotrophic lateral sclerosis, Parkinson’s disease, Prion diseases and Down syndrome. We are collaborating with neuroscientists in Australia, France, Spain, Italy, Germany, USA and Japan.
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Show details for [<FONT SIZE=2 FACE="Verdana"><b>]Professor Lisa Jackson Pulver[</b><br>&nbsp&nbsp&nbsp&nbsp<i>School of PublicProfessor Lisa Jackson Pulver
    School of Public Health and Community Medicine
    Statement of Interests:

    Research interests
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Dr Lee Krahe
    Rural Clinical School - Mid North Coast Division - Port Macquarie Campus
    Statement of Interests:
    Vascular and cardiovascular diseases are major factors in morbidity and mortality in patients with Type 2 diabetes. Studies have shown that lifestyle intervention, including diet and exercise, may halt the progression from impaired glucose tolerance to overt type 2 diabetes. The challenge for clinicians is implementation of research results into clinical practice. Developing an exercise prescription -achievable for patients in the 'everyday'- is one such research avenue worthy of pursuit.
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Dr Lee-Fay Low
    School of Psychiatry - Dementia Collaborative Research Centre
    Statement of Interests:

    Risk factors for cognitive decline and dementia, dementia literacy in the Australian population and in persons from culturally and linguistically diverse backgrounds, provision of services for persons with dementia, behavioural and psychological symptoms of dementia.
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Dr Rod McKay
    School of Public Health and Community Medicine
    Statement of Interests:

    Interest in the evaluation of mental health systems for the elderly and their effectiveness; and in the utilisation of routine outcome measurement to improve such systems. Current collaborative work with AMHOCN (Australian Mental Health Outcomes and Casemix Network) in developing a tool to support supervision using routine outcome measure results.
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Dr Litsa Morfis
    School of Public Health and Community Medicine
    Statement of Interests:

    The study of vascular diseases and their impact on cognitive decline in the elderly.
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Professor Tuan Van Nguyen
    School of Public Health and Community Medicine
    Statement of Interests:

    I have two main interests in osteoporosis research: epidemiology of osteoporotic fractures and genetics of osteoporosis. In terms of epidemiology, my group’s research interests are mainly in the study of determinants of fracture and the development of prognostic models for predicting fracture risk in an individual patient. A second focus of my group’s research is concerned with the genetics of osteoporosis. We are specifically interested in finding novel genes that are involved in the regulation of bone phenotypes, including bone mineral density and fracture. Current research projects: * Development of prognostic models for the assessment of fracture risk * Development of new phenotype for osteoporosis * Determinants of bone loss and the concept of risk individualization * Hormonal determinants of diabetes, cancer and osteoporosis * Bayesian models for epidemiologic data * Genomewide association study of osteoporosis genes * Genomewide linkage analysis of bone phenotypes I currently have a number of projects that are suitable for masters and PhD candidates. I am looking for candidates with strong background in clinical epidemiology, genetics, and biostatistics with solid knowledge in Bayesian modeling. Interested candidates can contact me via email at tuan.nguyen@unsw.edu.au or t.nguyen@garvan.org.au for more detailed description of these projects.
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Show details for [<FONT SIZE=2 FACE="Verdana"><b>]Dr Rema Oliver[</b><br>&nbsp&nbsp&nbsp&nbsp<i>Prince of Wales Clinical SchoolDr Rema Oliver
    Prince of Wales Clinical School
    Statement of Interests:
    Dr Rema Oliver, a full-time research fellow at the Surgical & Orthopaedic Research Laboratories, has for the past 9 years been investigating the biological process which occurs during fracture repair of both pathological (osteoporosis) and arthroplastic-induced foreign body reactions. Current research focuses upon the physiological consequences of osteoporosis especially in post-menopausal women. This work is carried out in collaboration with orthopaedic surgeons at the Prince of Wales Hospital.
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Dr Olivier Piguet
    Prince of Wales Medical Research Institute
    Statement of Interests:

    Current research projects focus on frontotemporal dementia (FTD), with a particular interest in the early clinical characteristics of the different subtypes of the disease and progression over time. Research projects generally combine different approaches cognitive testing, clinical interviews and questionnaires, brain imaging, and postmortem investigations. Emotion processing is impaired in FTD. How does it affect the ability to remember meaningful and important information from one’s life? How does it affect interpersonal relationships? How do these deficits evolve with time? These are some of the questions that currently unresolved. Funded by the National Health and Medical Research Council of Australia, this project follow patients with FTD who undergo tests of memory, language and thinking abilities and receive a brain MRI scan at yearly intervals. We also interview family members of patients to understand the impact of the disease on interpersonal relationships. FTD predominantly affects two regions of the brain: the frontal and temporal lobes. Presence of progressive change to these brain structures is an important feature of the disease and helps towards an accurate diagnosis. This project examines the extent and severity of changes taking place in the frontal and temporal lobes as the disease progresses in the grey and white matter of the brain. This project will contribute to our understanding of the progression of the disease and improve diagnostic accuracy.
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Associate Professor Nicholas Pocock
    St Vincent's Clinical School - Department of Medicine
    Statement of Interests:
    Diagnostic techniques for osteoporosis. Epidemiology of osteoporosis and impact on society.
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Dr Simone Reppermund
    School of Psychiatry
    Statement of Interests:
    My main research interests include cognitive functioning in depression and ageing, particularly to find predictors of the course of depression and age-related cognitive decline. I am study coordinator of the Memory and Ageing Study (MAS), a multifaceted population-based study bringing together neuropsychological, medical, brain imaging, genetic and proteomic components to identify risk factors, or even protective factors against developing dementia.
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Dr Joel Rhee
    School of Public Health and Community Medicine
    Statement of Interests:

    Primary care research focusing on advance care decision-making and planning. Primary palliative care research on barriers to GP involvement in palliative care.
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Dr Tuly Rosenfeld
    Prince of Wales Clinical School
    Statement of Interests:

    Emergency departments and the elderly; medications in the elderly; speech and nutrition in the elderly; swallowing disorders. Pre and Post Acute Care of Older People Pharmacy and Ageing
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Scientia Professor Perminder Sachdev
    School of Psychiatry
    Statement of Interests:
    There are broad interests in the field of Neuropsychiatry. Our major focus is on ageing and cognition,and I head the Brain and Ageing program. We have large longitudinal studies of ageing including: Memory and Ageing Study, Older Australian Twins Study, PATH Through Life Study, Sydney Centenarian Study and the Sydney Stroke Study. These studies examine MVI, Alzheimer's disease, Vascular Cognitive Impairment and Vascular Dementia, as well as Cognitive Ageing in healthy individuals. We have a number of studies that involve neuroimaging (MRI, MRS, pMRI, fMRI and SPECT) in dementia, mild cognitive impairment, fronto-temproal dementia, stroke, OCD, anorexia nervosa, etc. We also have a number of studies involving Transcranial Magnetic Stimulation (TMS) and transcranail direct current stimulation (tDCS) for both treatment and as an investigational tool in neuropsychology. We have an interest in exploring novel treatments, including Vagus Nerve Stimulation for depression. I am also the Executive Director of the Stem Cell Laboratory with a focus on neural stem cells.
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Dr Alison Short
    Australian Institute of Health Innovation - Centre for Clinical Governance Research in Health
    Statement of Interests:

    From a broad research experience base, interests include health communication, multidisciplinary research in the clinical setting, investigating the research needs of clinicians, links between noise and stress, multicultural issues, psychosocial effects of physical illness and treatment, and professional music therapy (including relaxation and mental imagery). This occurs within the context of clinical trials and audits, qualitative and mixed method research approaches and as linked to areas including aged care and graduate workforce issues.
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Dr David Simar
    School of Medical Sciences - Exercise Physiology Program
    Statement of Interests:
    My research interests are mainly focused on the characterisation of metabolic dysfunctions in the immune system and skeletal muscles as well as the critical role played by inflammation in the development of those alterations in metabolic and immune conditions.
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Dr Melissa Slavin
    School of Psychiatry
    Statement of Interests:

    I am a Research Fellow within the School of Psychiatry, working on a number of projects, including the Memory and Ageing Study, the Sydney Centenarian Study, and several neuroimaging projects. I am particularly interested in cerebrovascular damage and the impact of this on cognition.
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Dr George Smythe
    School of Medical Sciences - Department of Physiology
    Statement of Interests:

    Neurodegenerative diseases of aging such as Alzheimer's Disease are associated with oxidative and free radical-induced damage to DNA, proteins, and energy metabolism in the CNS, Of particular interest are diagnostic markers of this damage and the role of anti-oxidants, radical scavengers and metal chelators in attenuating the damage. Collaborative work with neuroscientists at St Vincent's and Prince of Wales Hospitals and Monash University is investigating Alzheimer's and other demeting diseases, Other collaborations with neuroscientists in the UK is investigating malaria-induced brain dysfunction.
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Ms Daina Sturnieks
    School of Medical Sciences
    Statement of Interests:

    Research interests include studies to understand human balance and walking, including sensory and motor contributions, as well as falls-related research in elderly populations.
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Dr Nick Titov
    School of Psychiatry
    Statement of Interests:
    I am involved in developing Internet-based education and treatment programs for common mental disorders. These programs target different age groups. With respect to my interests in mental health policy, I am exploring the uptake of evidence-informed techniques.
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Associate Professor Julian Trollor
    School of Psychiatry - Intellectual Disability Mental Health
    Statement of Interests:

    Research projects are available to suit a variety of students at the ILP, Honours, Masters and PhD level. There are 3 broad streams to my current research: 1. Brain Ageing: determinants and correlates of brain ageing with a focus on brain imaging, metabolic, cardiovascular and inflammatory factors, nutrition, and gene-environment inteactions. Study data is derived from two large ageing gohorts, the Sydney Memory and Ageing Study and the Older australian Twins Study. 2. Developmental Disability Neuropsychiatry: a number of focus areas including ageing and dementia in intellecutally disabled adults, intellecual disability mental health within the criminal justice system, human rights issues in health care of intellecually disabled adults. 3. Other Neuropsychaitric Disorders: I have an established interest in a variety of neuropsychaitric conditions including the neuropsychiatry of epilepsy, adult ADHD, novel treatments for depression (including VNS)and drug induced movement disorders including NMS.
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Dr Michael Valenzuela
    School of Psychiatry
    Statement of Interests:

    Dr Valenzuela is a Research Fellow in Regenerative Neuroscience at the School of Psychiatry, UNSW and the Neuropsychiatric Institute, Prince of Wales Hospital. His background is in psychology, clinical medicine and neuroscience research. His PhD focused on the topic of brain reserve, specifically how complex mental activity affects the development and expression of dementia. This question was tackled using a multi-modal and longitudinal approach, bringing together epidemiological, neuroimaging and biochemical techniques. For this work he was awarded the prestigious Eureka Prize for Medical Research in 2006. Dr Valenzuela’s current research interests are aimed at further understanding the competing forces of neuroplasticity and neurodegeneration in the human brain, and how these can either lead to, or help prevent, dementia. He is working on a range of studies across various technologies, including in vivo brain imaging, post-mortem brain tissue analysis, neural stem cell culture, and animal behaviour. Dr Valenzuela also believes that the problem of dementia is a critical one for modern society, and is committed to communicating dementia-prevention health ideas to the public.
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Associate Professor Judie Walton
    St George Clinical School - Department of Surgery
    Statement of Interests:

    As Director of Clinical Outcomes Research for the Orthopaedic Research Institute, I am involved in a variety of clinical research activities, aiming to contribute to evidence-based medicine in orthopaedics and sports medicine through controlled studies to probe the efficacy of diagnostic tests, surgical outcomes, and how intensive training regimes affect the health of athletes. In addition, I have research interests in cell biology, primarily involving the etiologies of osteoporosis and other age-related disease conditions.
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    Statement of Interests:

    The broad aim of my research is to understand the physiology of the nervous system involved in the control of movement, and to determine how this system changes with ageing, injury and disease. My specific research interests concern the neural mechanisms controlling the activation patterns for groups of muscles and the role of strength training, ageing, fatigue and injuries in altering these patterns of muscle coordination. The goal of my research program is to better understand these acute and chronic adaptations of the human neuromuscular system to help improve clinical practice in the areas of injury prevention and rehabilitation. The motor system of human subjects is examined using the techniques of electromyography and nerve stimulation to measure the activity of single motor units and spinal reflex pathways. In conjunction with these techniques, servo-controlled torque motors are used to provide experimental manipulations of load characteristics and to deliver perturbations to movement. Current projects: characterising the neural pathways coupling the knee extensor muscles.
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