Research Interests
Associate Professor Paul Bertrand |
| (Position Details) |
| Phone 02 9385-3947 |
| Email |
| Qualifications BSc (MSU) Zoology (Neurophysiology), PhD (MSU) Pharmacology & Toxicology |
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| School/Unit |
| School of Medical Sciences |
| http://medicalsciences.med.unsw.edu.au/SOMSWeb.nsf/page/Enjoyable+Gut+Neuroscience
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| Broad Research Areas | |
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Neuroscience
Gastrointestinal Diseases
Physiology
Pharmacology
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| Specific Research Keywords | |
| Electrophysiology
ATP
Sensory Mechanisms
Synaptic Transmission in the Enteric Nervous System
Serotonin
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| Research Interests | |
| The goal of my research is to understand the neuronal basis of disease with an emphasis on the compounds ATP & serotonin (5‑HT) and the roles they play in neurotransmission & sensory transduction. My laboratory focuses on the neurophysiology of the gastrointestinal tract using electrophysiological and electrochemical methods.
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| ILP Research Interests (Will supervise ILP students) |
| Autonomic Agents
Central Nervous System Agents
Digestive System
Digestive System Diseases
Electrophysiology
Gastroenterology
Gastrointestinal Diseases
Gastrointestinal System
Immunochemistry
Inflammation
Medicine
Molecular Biology
Nervous System Diseases
Neurons
Neurophysiology
Neurosecretory Systems
Neurotoxins
Neurotransmitter Agents
Neurotransmitters
Peripheral Nerve Diseases
Peripheral Nerves
Pharmacology
Physiology
Selective Serotonin Reuptake Inhibitors
Sense Organs
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| Teaching Interests | |
| Basic neuroscience, ion channels and G-protein coupled receptors, gastrointestinal function and control. | |
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| Society Memberships & Professional Activities | |
| ASPET - American Society for Pharmacology and Experimental Therapeutics
(since 1992)
SFN - Society for Neuroscience (since 1993)
ANS - Australian Neuroscience Society (since 1995)
APS - American Physiological Society (since 1998)
NARF - National Association of Research Fellows (since 1998)
AGA - American Gastroenterological Association (since 2003)
EMS - European Motility Society (since 2004)
AMS - American Motility Society (since 2005)
SC - Serotonin Club
AuPS - Australian Physiological Society
ASCEPT - Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists | |
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| Funding Sources | |
| NH&MRC Project grant (2008-2010) | |
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| Key works/Publications | |
| Monro, R.L., Bornstein, J.C. and Bertrand, P.P. (2008). Synaptic Transmission from the Submucous Plexus to the Myenteric Plexus in Guinea-Pig Ileum. Neurogastroenterology and Motility. In press. doi: 10.1111/j.1365-2982.2008.01157.x
Bertrand, P.P. and Bian, X.-C. (2008). From 'macro' to 'micro': mapping the neuronal circuits of the intestine. Clinical and Experimental Pharmacology and Physiology. Jul;35(7):715-6.
Ren, J. and Bertrand, P.P. (2007). Purinergic receptors and synaptic transmission. Purinergic Signalling. DOI 10.1007/s11302-007-9088-5.
Bertrand P.P. (2007). A new role for P2 receptors: talking with calcium-activated potassium channels. Neurogastroenterol Motil. 19(11):865-8.
Bertrand, P. P. and Bertrand, R. L. (2007). Teaching gastrointestinal motility using classic papers by Dr. Walter B. Cannon. Advances in Physiology Education. 31(2): 136-9.
Bertrand, P. P., (2006). Real-time measurement of serotonin release and motility in guinea pig ileum. Journal of Physiology. 577(2): 689-704.
Bertrand, P.P. (2004). Real-time detection of serotonin release from enterochromaffin cells of the guinea pig ileum. Neurogastroenterology and Motility 16(5): 511-514 .
Bertrand, P. P. (2003). ATP and Sensory Transduction in the Enteric Nervous System. The Neuroscientist. 9(4):243-60.
Bertrand, P. P. and Bornstein, J. C. (2002). ATP as a putative sensory mediator: activation of intrinsic sensory neurons of the myenteric plexus via P2X receptors. Journal of Neuroscience 22(12): 4767-4775. | |
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| Further Information | |
| http://paul-bertrand.com/ | |
Profile last updated: 6/06/2008
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