The efficacy of an integrated treatment for post traumatic stress disorder (PTSD) and substance use disorders
NDARC Staff
Katherine Mills, Maree Teesson, Claudia Sannibale, Emma Barrett, Philippa Farrugia, Sabine Merz and Julia Rosenfeld
Other Investigators
Amanda Baker (University of Newcastle); Sally Hopwood (Centre for Traumatic Stress, Westmead Hospital); Sudie Back (Medical University of South Carolina, USA); Kathleen Brady (Medical University of South Carolina, USA)
Aims
The present study is one of the first randomised controlled trial to examine the efficacy of an integrated therapy for PTSD and substance use disorders.
Specifically, the aims of the study are to:
- evaluate the efficacy of an integrated intervention for PTSD and substance use disorders by comparing the treatment outcomes of those who receive the intervention with those who receive standard care for their substance use
- identify factors that influence the efficacy of the integrated intervention including:
- subject characteristics: demographic, substance use and psychological factors
- treatment characteristics: treatment compliance
- to assess the feasibility of implementing the intervention as measured by treatment retention and client satisfaction
Design and Method
A randomised controlled trial is being conducted to address the research aims. One-hundred and three participants were recruited from alcohol and other drug treatment services in greater Sydney and via advertisements. Participants were randomised to one of two groups stratified according to sex: (i) those who receive the intervention (n=55), and (ii) those who receive standard care (n=48).
The intervention is a modified version of Concurrent Treatment of PTSD and Substance Dependence developed in the United States. The intervention consists of thirteen, 90 minute sessions involving cognitive behavioural therapy with exposure techniques. Attempts are made to follow-up all participants at 6 weeks, 3 months and 9 months post baseline. Baseline and follow-up interviews include validated instruments to measure demographics, substance use and dependence, substance use and PTSD treatment history, criminal involvement, general physical and mental health, trauma exposure and PTSD, depression, anxiety, borderline personality disorder, and health service utlisation.
Progress
Participants were recruited from April 2007 – June 2009. Follow-up of participants is continuing.
Funding
National Health and Medical Research Council and NSW Health